Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.43 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713412 | 0.87 | PTGS2 (0.50) | NPSR1HSD17B10MAPTTP53POLB | |
| SCHEMBL10842542 | 0.80 | NPSR1 (0.75) | NPSR1HSD17B10MAPTTP53MAPK1 | |
| SCHEMBL6713346 | 0.79 | LMNA (0.58) | NPSR1HSD17B10LMNAALDH1A1PPARG | |
| SCHEMBL3371820 | 0.79 | EPHX2 (0.45) | NPSR1EPHX2MAPTPOLBMAPK1 | |
| SCHEMBL2672619 | 0.77 | MMP8 (0.54) | NPSR1EPHX2MAPTTP53HPGD | |
| SCHEMBL5145087 | 0.76 | TP53 (0.42) | NPSR1HSD17B10EPHX2MAPTTP53 | |
| SCHEMBL2551616 | 0.75 | EPHX2 (0.52) | NPSR1EPHX2MAPTHPGDLMNA | |
| SCHEMBL25403051 | 0.74 | MMP8 (0.55) | NPSR1EPHX2MAPTTP53HPGD | |
| SCHEMBL6365766 | 0.74 | EPHX2 (0.51) | NPSR1EPHX2MAPTPOLBHPGD | |
| SCHEMBL21117877 | 0.74 | EPHX2 (0.51) | NPSR1EPHX2MAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1956949-A | Substituted sulfonamides | MERCK & CO INC (US) | 2007-05-02 | — | — | CN | disclosed |