SCHEMBL2766733

SCHEMBL2766733

CC(n1ccc(-c2ccccc2)n1)(n1ccc(-c2ccccc2)n1)n1ccc(-c2ccccc2)n1.Cl[Mn]Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.38
KEAP1 Q14145 1/20 0.37
KDM4E B2RXH2 4/20 0.36
HSD17B10 Q99714 2/20 0.36
RAB9A P51151 6/20 0.34
NPC1 O15118 5/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
TP53 P04637 2/20 0.34
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
ALOX15 P16050 1/20 0.34
SCN9A Q15858 2/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
MAPT P10636 3/20 0.33
LMNA P02545 2/20 0.33
ALDH1A2 O94788 1/20 0.33
ALDH1A3 P47895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2454577 0.93 KMT2A (0.59) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL2766839 0.85 KEAP1 (0.40) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL13045974 0.82 KMT2A (0.59) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL21323197 0.79 KMT2A (0.55) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL28835950 0.78 KMT2A (0.53) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL28109887 0.76 KMT2A (0.55) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL6438456 0.74 KMT2A (0.53) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL4982785 0.74 KMT2A (0.53) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL2766813 0.74 KMT2A (0.48) KMT2AMEN1KEAP1KDM4EHSD17B10
SCHEMBL2765520 0.73 ALDH1A1 (0.34) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266911-B1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-6881802-B2 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-02-13 US disclosed
EP-1266911-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer BRAP, MCM4, BOLA2; BOLA2B KMT2A 1204/4885MEN1 632/4885KEAP1 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.