Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859237 | 0.87 | ADORA3 (0.40) | ADORA3SLC6A3ALDH1A1 | |
| SCHEMBL27718942 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28761626 | 0.75 | MAPK1 (0.31) | — | |
| SCHEMBL998820 | 0.73 | HTT (0.51) | ADORA3SLC6A3ALDH1A1MEN1KMT2A | |
| SCHEMBL27593641 | 0.72 | ALDH1A1 (0.39) | TDP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL27951598 | 0.69 | CHRM2 (0.36) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27788104 | 0.69 | CHRM2 (0.50) | ADORA3SLC6A3TDP1KDM4E | |
| SCHEMBL27669965 | 0.68 | ADRA2C (0.42) | TDP1ALDH1A1 | |
| SCHEMBL27593507 | 0.67 | CHRM2 (0.39) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27845916 | 0.67 | SMN1; SMN2 (0.40) | ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910166-A | Heteroaryl ureas and their use as glucokinase activators | NOVO NORDISK AS (DK) | 2007-02-07 | — | — | CN | disclosed |