Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28229934 | 0.82 | MTNR1A (0.55) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27570842 | 0.79 | MTNR1A (0.40) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27585383 | 0.77 | MTNR1A (0.44) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27807046 | 0.76 | CHRM2 (0.44) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27312907 | 0.76 | MTNR1A (0.41) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27844281 | 0.75 | MTNR1A (0.49) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27570669 | 0.75 | MTNR1A (0.40) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27799208 | 0.74 | MTNR1A (0.46) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16222838 | 0.72 | HTR2A (0.57) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27478880 | 0.72 | SRD5A1 (0.39) | MTNR1ACHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906180-A | New long acting beta-2-agonists and their use as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2007-01-31 | — | — | CN | disclosed |