Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585383 | 0.85 | MTNR1A (0.44) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL28491796 | 0.83 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL28229934 | 0.81 | MTNR1A (0.55) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27570842 | 0.81 | MTNR1A (0.40) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27312907 | 0.78 | MTNR1A (0.41) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27570669 | 0.77 | MTNR1A (0.40) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27844281 | 0.77 | MTNR1A (0.49) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27929079 | 0.77 | SRD5A1 (0.39) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27478880 | 0.77 | SRD5A1 (0.39) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27799208 | 0.77 | MTNR1A (0.46) | CHRM2CHRM4CHRM1CHRM3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101754761-A | compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents | REVIVA PHARMACEUTICALS INC | 2010-06-23 | — | — | CN | disclosed |