Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27687586 | 0.85 | KDM4E (0.42) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL27668652 | 0.77 | MAPK1 (0.49) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL28765859 | 0.70 | MAPK1 (0.47) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL29538698 | 0.69 | ALDH1A1 (0.84) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL5414934 | 0.69 | GLA (0.53) | ALDH1A1KDM4EPOLBPKMHTT | |
| SCHEMBL27687686 | 0.69 | AVPR2 (0.50) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL21515338 | 0.68 | CHRM2 (0.74) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL27004711 | 0.66 | ALDH1A1 (0.66) | ALDH1A1KDM4EPOLBPKMKMT2A | |
| SCHEMBL1545217 | 0.66 | SMN1; SMN2 (0.70) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL8343388 | 0.65 | NOTUM (0.83) | ALDH1A1KDM4EPOLBPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922141-A | Novel heterocyclic compound | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-02-28 | — | — | CN | disclosed |