Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668652 | 0.93 | MAPK1 (0.49) | MAPK1RECQLMEN1HTTKMT2A | |
| SCHEMBL27687686 | 0.91 | AVPR2 (0.50) | MAPK1RECQLMEN1HTTKMT2A | |
| SCHEMBL27687596 | 0.83 | LMNA (0.45) | MAPK1ALDH1A1POLBKDM4EALOX15 | |
| SCHEMBL27668682 | 0.75 | TSHR (0.46) | MEN1HTTKMT2AALDH1A1POLB | |
| SCHEMBL5431239 | 0.73 | HTT (0.51) | MEN1HTTKMT2AALDH1A1POLB | |
| SCHEMBL27668669 | 0.70 | ALDH1A1 (0.49) | MEN1HTTKMT2AALDH1A1POLB | |
| SCHEMBL18292700 | 0.70 | POLB (0.78) | MAPK1MEN1HTTKMT2AALDH1A1 | |
| SCHEMBL29538698 | 0.66 | ALDH1A1 (0.84) | MEN1HTTKMT2AALDH1A1POLB | |
| SCHEMBL29598108 | 0.65 | POLB (0.70) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL27197571 | 0.65 | POLB (0.70) | MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922141-A | Novel heterocyclic compound | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-02-28 | — | — | CN | disclosed |