Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668669 | 0.85 | ALDH1A1 (0.49) | KDM4EPOLBGAAALDH1A1TSHR | |
| SCHEMBL27668682 | 0.74 | TSHR (0.46) | KDM4EPOLBGAAALDH1A1TSHR | |
| SCHEMBL5419233 | 0.69 | MEN1 (0.45) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27687596 | 0.68 | LMNA (0.45) | KDM4EPOLBGAAALDH1A1TSHR | |
| SCHEMBL27849798 | 0.68 | MEN1 (0.48) | KDM4EPOLBGAAALDH1A1TSHR | |
| SCHEMBL15001867 | 0.62 | SMN1; SMN2 (0.53) | KDM4EPOLBGAAALDH1A1TSHR | |
| SCHEMBL22784252 | 0.62 | NOTUM (0.64) | KDM4EPOLBGAAALDH1A1TSHR | |
| SCHEMBL4416703 | 0.62 | HDAC3 (0.63) | KDM4EGAAALDH1A1TSHRMEN1 | |
| SCHEMBL4416700 | 0.62 | MEN1 (0.58) | KDM4EGAAALDH1A1TSHRMEN1 | |
| SCHEMBL24925843 | 0.61 | RIPK1 (0.65) | KDM4EALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922141-A | Novel heterocyclic compound | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-02-28 | — | — | CN | disclosed |