Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087599 | 0.90 | LMNA (0.56) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| SCHEMBL7268383 | 0.86 | ALDH1A1 (0.62) | SLC1A1SLC1A3IDO1ALDH1A1KMT2A | |
| SCHEMBL10678429 | 0.86 | SLC1A1 (0.54) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7268375 | 0.85 | ALDH1A1 (0.60) | SLC1A1SLC1A3IDO1ALDH1A1KMT2A | |
| SCHEMBL14196105 | 0.84 | SLC1A1 (0.48) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| SCHEMBL27881559 | 0.84 | CYP1A2 (0.53) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| SCHEMBL9544573 | 0.84 | CYP1A2 (0.53) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| SCHEMBL10441465 | 0.83 | IDO1 (0.53) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| SCHEMBL4161005 | 0.83 | IDO1 (0.53) | LMNASLC1A1SLC1A3IDO1ALDH1A1 | |
| SCHEMBL4989088 | 0.83 | LTA4H (0.48) | SLC1A1SLC1A3IDO1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1946727-B | (Poly) aminoacetamide derivatives of epipodophyllotoxin, their process of preparation and their applications in therapeutics as anticancer agents | PF MEDICAMENT | 2010-08-11 | — | — | CN | disclosed |
| CN-1946727-A | (Poly) aminoacetamide derivatives of epipodophyllotoxin their process of preparation and their applications in therapeutics as anticancer agents | PF MEDICAMENT (FR) | 2007-04-11 | — | — | CN | disclosed |