Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194066 | 1.00 | TDP1 (0.50) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL2159141 | 0.86 | LMNA (0.59) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL8745550 | 0.86 | LMNA (0.59) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL2159137 | 0.86 | LMNA (0.59) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL28169679 | 0.85 | TDP1 (0.47) | TDP1LMNAGAASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL11195536 | 0.84 | LMNA (0.57) | TDP1LMNAGAASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL11195541 | 0.84 | LMNA (0.57) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL868433 | 0.83 | CA12 (0.45) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL625123 | 0.83 | CA12 (0.45) | TDP1LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL11201043 | 0.82 | MAPT (0.49) | TDP1LMNAGAASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816337-A | Naphthalene-containing melanocortin receptor-specific small molecule | PALATIN TECHNOLOGIES INC (US) | 2006-08-09 | — | — | CN | disclosed |