Sugi Predict

Sugi Predict / Compounds / SCHEMBL625123

SCHEMBL625123

SCHEMBL625123

O=C(O)C(Nc1ccccc1)C(O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 1/20 0.45
▸ CA9 Q16790 1/20 0.45
▸ LMNA P02545 4/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ HPGD P15428 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ TSHR P16473 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ EPHX1 P07099 1/20 0.43
▸ EPHX2 P34913 1/20 0.43
▸ CDK9 P50750 1/20 0.43
▸ CLK4 Q9HAZ1 1/20 0.43
▸ ALDH1A1 P00352 3/20 0.42
▸ HSD17B10 Q99714 3/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868433 1.00 CA12 (0.45) CA12CA9LMNASMN1; SMN2HPGD
SCHEMBL30564492 0.85 CA12 (0.44) CA12CA9LMNASMN1; SMN2HPGD
SCHEMBL28812355 0.84 CA12 (0.47) CA12CA9LMNASMN1; SMN2HPGD
Benzene SCHEMBL27670933 0.83 TDP1 (0.50) CA12CA9LMNASMN1; SMN2HPGD
SCHEMBL11194066 0.83 TDP1 (0.50) CA12CA9LMNASMN1; SMN2HPGD
SCHEMBL28717180 0.82 LMNA (0.47) CA12CA9LMNATSHRALDH1A1
SCHEMBL28717182 0.82 LMNA (0.47) CA12CA9LMNATSHRALDH1A1
SCHEMBL3876430 0.81 MAPT (0.47) CA12CA9LMNASMN1; SMN2HPGD
SCHEMBL8745550 0.81 LMNA (0.59) LMNASMN1; SMN2HPGDGAATSHR
SCHEMBL2159141 0.81 LMNA (0.59) LMNASMN1; SMN2HPGDGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004058210-A1 COSMETIC COMPOSITION CONTAINING A MELANIN PRECURSOR UNILEVER PLC (GB) 2004-07-15 — — WO claimed
WO-2025024553-A1 APPLICATIONS AND BIOSYNTHESIS OF CYANOBACTERIAL COMPOUNDS SUNECO TECHNOLOGIES INC. (US) 2025-01-30 — — WO disclosed
CN-118374475-A Novel CRISPR related transposase and application thereof 孟山都技术公司 2024-07-23 — — CN disclosed
CN-118374474-A Novel CRISPR related transposase and application thereof 孟山都技术公司 2024-07-23 — — CN disclosed
US-20240173258-A1 LIPOSOME COMPOSITIONS AND METHODS OF USE THEREOF UNIV OF RHODE ISLAND BOARD OF TRUSTEES (US) 2024-05-30 — — US disclosed
US-11857509-B2 Liposome compositions and methods of use thereof UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2024-01-02 — — US disclosed
CN-114181960-A Chimeric antigen receptors and methods of use 美天施生物科技有限公司 2022-03-15 — — CN disclosed
US-11229710-B2 Environmentally sensitive compositions comprising a pH-triggered membrane protein and methods of use thereof in the treatment and diagnosis of tumors UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2022-01-25 — — US disclosed
CN-108779162-B Chimeric antigen receptors and methods of use 美天施生物科技有限公司 2021-12-07 — — CN disclosed
CN-113754755-A T cell receptor recognizing MHC class II restricted MAGE-A3 美国政府卫生与公众服务部 2021-12-07 — — CN disclosed
EP-1680435-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES Cognis IP Management GmbH (DE) 2006-07-19 — — EP disclosed
CN-1803124-A Gamma-polyglutamic acid, gamma-polyglutamate and application of hydrogel thereof EAST SEA BIOTECHNOLOGY CO LTD (CN) 2006-07-19 — — CN disclosed
US-20060009550-A1 Polymeric compositions and related methods of use NIH - DEITR 2006-01-12 — — US disclosed
US-20050288398-A1 Polymeric compositions and related methods of use NIH - DEITR 2005-12-29 — — US disclosed
WO-2005118831-A2 POLYMERIC COMPOSITIONS AND RELATED METHODS OF USE NORTHWESTERN UNIVERSITY (US) 2005-12-15 — — WO disclosed
CN-1217644-C Beauty and skin composition containing plant extract OREAL (FR) 2005-09-07 — — CN disclosed
WO-2005049633-A1 ACYL RIBONUCLEOSIDES AND ACYL DEOXYRIBONUCLEOSIDES COGNIS IP MANAGEMENT GMBH (DE) 2005-06-02 — — WO disclosed
US-20040018259-A1 Use of at least one extract of a plant of the genus lannea in a cosmetic or dermopharmaceutical composition PAULY GILLES (FR) 2004-01-29 — — US disclosed
US-6599537-B1 Antiradical, cytophotoprotective, tyrosinase and melanogenesis inhibiting and antiprotease effects COGNIS FRANCE S.A. (FR) 2003-07-29 — — US disclosed
CN-1261528-A Beauty and skin composition containing plant extract OREAL (FR) 2000-08-02 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11229710-B2 Environmentally sensitive compositions comprising a pH-triggered membrane protein and methods of use thereof in the treatment and diagnosis of tumors PHLPP1, PHLPP2, GHITM CA12 140/4885CA9 167/4885LMNA 2435/4885
US-20240173258-A1 LIPOSOME COMPOSITIONS AND METHODS OF USE THEREOF LIPA, PHLPP1, PHLPP2 CA12 3161/4885CA9 3525/4885LMNA 669/4885
US-11857509-B2 Liposome compositions and methods of use thereof LIPA, PHLPP1, PHLPP2 CA12 3161/4885CA9 3525/4885LMNA 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.