Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625123 | 1.00 | CA12 (0.45) | CA12CA9LMNASMN1; SMN2HPGD | |
| SCHEMBL30564492 | 0.85 | CA12 (0.44) | CA12CA9LMNASMN1; SMN2HPGD | |
| SCHEMBL28812355 | 0.84 | CA12 (0.47) | CA12CA9LMNASMN1; SMN2HPGD | |
| Benzene SCHEMBL27670933 | 0.83 | TDP1 (0.50) | CA12CA9LMNASMN1; SMN2HPGD | |
| SCHEMBL11194066 | 0.83 | TDP1 (0.50) | CA12CA9LMNASMN1; SMN2HPGD | |
| SCHEMBL28717180 | 0.82 | LMNA (0.47) | CA12CA9LMNATSHRALDH1A1 | |
| SCHEMBL28717182 | 0.82 | LMNA (0.47) | CA12CA9LMNATSHRALDH1A1 | |
| SCHEMBL3876430 | 0.81 | MAPT (0.47) | CA12CA9LMNASMN1; SMN2HPGD | |
| SCHEMBL8745550 | 0.81 | LMNA (0.59) | LMNASMN1; SMN2HPGDGAATSHR | |
| SCHEMBL2159141 | 0.81 | LMNA (0.59) | LMNASMN1; SMN2HPGDGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119744300-A | Enzyme with D-amino acid synthesis activity and application thereof | 武汉远大弘元股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| WO-2024077428-A1 | ENZYME WITH D-AMINO ACID SYNTHESIS ACTIVITY AND USE THEREOF | 武汉远大弘元股份有限公司 | 2024-04-18 | — | — | WO | disclosed |
| US-10221435-B2 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | MITSUI CHEMICALS, INC. (JP) | 2019-03-05 | — | — | US | disclosed |
| US-20170327853-A1 | DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2017-11-16 | — | — | US | disclosed |
| US-9695452-B2 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | MITSUI CHEMICALS, INC. (JP) | 2017-07-04 | — | — | US | disclosed |
| EP-2295566-B1 | Method of producing D-serine by using a microbial D-serine synthase. | MITSUI CHEMICALS INC (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-2602319-B1 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | MITSUI CHEMICALS INC (JP) | 2016-12-07 | — | — | EP | disclosed |
| EP-2602320-B1 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | MITSUI CHEMICALS INC (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-20160046970-A1 | DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2016-02-18 | — | — | US | disclosed |
| US-9212376-B2 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | MITSUI CHEMICALS, INC. (JP) | 2015-12-15 | — | — | US | disclosed |
| EP-1806401-B1 | DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME | MITSUI CHEMICALS INC (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2602320-A1 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | Mitsui Chemicals, Inc. (JP) | 2013-06-12 | — | — | EP | disclosed |
| EP-2602319-A1 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | Mitsui Chemicals, Inc. (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-20120077233-A1 | DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2012-03-29 | — | — | US | disclosed |
| US-7919285-B2 | DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same | MITSUI CHEMICALS, INC. (JP) | 2011-04-05 | — | — | US | disclosed |
| EP-2295566-A1 | Method of producing D-serine by using a microbial D-serine synthase. | Mitsui Chemicals, Inc. (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-20080293098-A1 | Dna Encoding Novel Enzyme Having D-Serine Synthase Activity, Method of Producing the Enzyme and Method of Producing D-Serine by Using the Same | MITSUI CHEMICALS, INC. (JP) | 2008-11-27 | — | — | US | disclosed |
| EP-1806401-A1 | DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |