Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059958 | 0.81 | TAAR1 (0.57) | MAPTKDM4EALDH1A1BLMSMARCA2 | |
| SCHEMBL27651185 | 0.77 | KDM4E (0.47) | MAPTKDM4EALDH1A1TAAR1HSD17B10 | |
| SCHEMBL1701227 | 0.74 | PTGS1 (0.42) | MAPTKDM4EALDH1A1BLMSMARCA2 | |
| SCHEMBL2646425 | 0.71 | MAPT (0.50) | MAPTKDM4EALDH1A1BLMSMARCA2 | |
| SCHEMBL27715112 | 0.71 | MAPT (0.44) | MAPTKDM4EALDH1A1BLMSMARCA2 | |
| SCHEMBL1445860 | 0.69 | MIF (0.52) | MAPTKDM4EALDH1A1BLMSMARCA2 | |
| SCHEMBL17742751 | 0.69 | PDE10A (0.50) | MAPTKDM4EALDH1A1BLMHSD17B10 | |
| SCHEMBL13472357 | 0.68 | KMO (0.63) | KDM4EALDH1A1 | |
| SCHEMBL14910966 | 0.67 | ASIC3 (0.53) | MAPTKDM4EALDH1A1BLMSMARCA2 | |
| SCHEMBL17777363 | 0.67 | ADORA2B (0.49) | MAPTKDM4EALDH1A1BLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942469-B | Condensed pyridine derivatives useful as A28 adenosine receptor antagonists | ALMIRALL LAB | 2010-07-07 | — | — | CN | disclosed |
| CN-1942469-A | Condensed pyridine derivatives useful as A28 adenosine receptor antagonists | ALMIRALL LAB (ES) | 2007-04-04 | — | — | CN | disclosed |