Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 6/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651618 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL27671840 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL27736398 | 0.79 | MTNR1A (0.33) | MTNR1AMTNR1BALDH1A1ACACBACACA | |
| SCHEMBL27740374 | 0.78 | CYP2D6 (0.39) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL18394986 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL18395917 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL18395913 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL18394981 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL795359 | 0.78 | ALDH1A1 (0.45) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL2766000 | 0.78 | ALDH1A1 (0.45) | MTNR1AMTNR1BALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1898234-A | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORP (US) | 2007-01-17 | — | — | CN | disclosed |