Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982970 | 0.80 | PDE4D (0.47) | SMN1; SMN2HRH4HRH3TDP1L3MBTL1 | |
| SCHEMBL8668088 | 0.78 | ALDH1A1 (0.66) | ALDH1A1PTGER1HTTSMN1; SMN2LMNA | |
| SCHEMBL291607 | 0.78 | FOLH1 (0.54) | ALDH1A1HTTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL8667447 | 0.77 | ALDH1A1 (0.64) | ALDH1A1PTGER1HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL21753093 | 0.77 | FOLH1 (0.51) | ALDH1A1PTGER1HTTSMN1; SMN2TSHR | |
| SCHEMBL30128417 | 0.77 | FOLH1 (0.51) | ALDH1A1PTGER1HTTSMN1; SMN2TSHR | |
| SCHEMBL28915593 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HTTSMN1; SMN2TSHRTDP1 | |
| SCHEMBL27331130 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HTTSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL940728 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2HRH4HRH3 | |
| SCHEMBL940642 | 0.76 | FFAR1 (0.44) | ALDH1A1HTTSMN1; SMN2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1894244-A | Aryl ether substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2007-01-10 | — | — | CN | disclosed |