Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940728 | 0.84 | ALDH1A1 (0.53) | FFAR1TDP1L3MBTL1FOLH1LMNA | |
| SCHEMBL23908388 | 0.79 | ALDH1A1 (0.49) | FFAR1FOLH1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30722451 | 0.77 | ALDH1A1 (0.47) | FFAR1FOLH1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29167354 | 0.77 | ALDH1A1 (0.47) | FFAR1FOLH1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL12913003 | 0.76 | TDP1 (0.45) | TDP1L3MBTL1LMNAALDH1A1HTT | |
| SCHEMBL27673045 | 0.76 | ALDH1A1 (0.49) | TDP1L3MBTL1LMNAALDH1A1HTT | |
| SCHEMBL10598359 | 0.75 | KAT8 (0.60) | TDP1L3MBTL1LMNAALDH1A1KAT8 | |
| SCHEMBL29687321 | 0.75 | KAT8 (0.45) | ALDH1A1HNF4AKAT8 | |
| SCHEMBL23092123 | 0.75 | KAT8 (0.45) | ALDH1A1HNF4AKAT8 | |
| SCHEMBL13715184 | 0.75 | HNF4A (0.67) | LMNAALDH1A1HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776345-B1 | Method of preparing N2-functionalised indazolinone derivatives | UNIV ST ANDREWS (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
| EP-1776345-A2 | A MULTICORE INDAZOLINONE LIBRARY | The University Court of the University of St. Andrews (GB) | 2007-04-25 | — | — | EP | disclosed |
| WO-2005121096-A2 | A MULTICORE INDAZOLINONE LIBRARY | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179294-A1 | Multicore indazolinone library | IPMK, TTK, IWS1 | FFAR1 4858/4885TDP1 2701/4885L3MBTL1 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.