Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653145 | 0.83 | KDM4E (0.40) | RETHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL27673156 | 0.82 | KDM4E (0.43) | RETGPR3LIMK1ALKBH5FTO | |
| SCHEMBL27653208 | 0.81 | RET (0.50) | RETGPR3HSD17B10L3MBTL1PABPC1 | |
| SCHEMBL27653075 | 0.80 | RET (0.46) | RETGPR3LIMK1ALKBH5FTO | |
| SCHEMBL3875323 | 0.79 | GPR3 (0.48) | GPR3LIMK1ALKBH5FTOHSD17B10 | |
| SCHEMBL28762588 | 0.79 | RET (0.51) | RETGPR3LIMK1ALKBH5FTO | |
| SCHEMBL16414205 | 0.77 | ALKBH5 (0.61) | GPR3LIMK1ALKBH5FTOHSD17B10 | |
| SCHEMBL28532001 | 0.76 | L3MBTL1 (0.35) | GPR3LIMK1ALKBH5FTOHSD17B10 | |
| SCHEMBL30586165 | 0.76 | L3MBTL1 (0.35) | GPR3LIMK1ALKBH5FTOHSD17B10 | |
| SCHEMBL27653085 | 0.76 | PABPC1 (0.54) | RETGPR3LIMK1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |