Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877515 | 0.80 | PKM (0.53) | MAPTALDH1A1POLBHCRTR1LMNA | |
| SCHEMBL27673165 | 0.77 | MAPT (0.41) | MAPTALDH1A1POLBALOX5HCRTR1 | |
| SCHEMBL3887852 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1POLBHCRTR1LMNA | |
| SCHEMBL23690476 | 0.75 | ALOX5 (0.43) | MAPTALDH1A1POLBALOX5HCRTR1 | |
| SCHEMBL3874443 | 0.75 | PKM (0.53) | MAPTALDH1A1POLBHCRTR1LMNA | |
| SCHEMBL3887742 | 0.73 | ALDH1A1 (0.47) | MAPTALDH1A1POLBALOX5HCRTR1 | |
| SCHEMBL3875198 | 0.72 | MAPT (0.46) | MAPTALDH1A1POLBALOX5HCRTR1 | |
| SCHEMBL3882583 | 0.71 | ALDH1A1 (0.44) | MAPTALDH1A1POLBHCRTR1LMNA | |
| SCHEMBL3886209 | 0.70 | IDO1 (0.47) | MAPTALDH1A1POLBALOX5HCRTR1 | |
| SCHEMBL3876524 | 0.69 | IDO1 (0.48) | MAPTALDH1A1POLBALOX5HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |