Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.43 |
| ▸ | WEE1 | P30291 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886228 | 0.82 | IMPDH2 (0.59) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL27673145 | 0.81 | CDK4 (0.47) | IMPDH2IMPDH1CHEK1WEE1CDK4 | |
| SCHEMBL27653109 | 0.80 | IMPDH2 (0.72) | IMPDH2IMPDH1CHEK1WEE1CDK4 | |
| SCHEMBL30565440 | 0.80 | IMPDH2 (0.72) | IMPDH2IMPDH1CHEK1WEE1CDK4 | |
| SCHEMBL27673124 | 0.79 | APP (0.44) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| Carbazole SCHEMBL27571745 | 0.78 | ALDH1A1 (0.64) | IMPDH2IMPDH1CHEK1WEE1CA1 | |
| SCHEMBL28762585 | 0.78 | IMPDH2 (0.50) | IMPDH2IMPDH1CHEK1WEE1CDK4 | |
| SCHEMBL27653234 | 0.77 | IMPDH2 (0.57) | IMPDH2IMPDH1CHEK1WEE1CDK4 | |
| SCHEMBL3881310 | 0.75 | CDK4 (0.51) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL27673106 | 0.74 | PARP1 (0.47) | IMPDH2IMPDH1CHEK1WEE1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |