Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 4/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762586 | 0.75 | ALOX5 (0.36) | MAPTTP53HTTKDM4EGAA | |
| SCHEMBL27673157 | 0.72 | ALOX5 (0.36) | MAPTTP53HTTKDM4EGAA | |
| SCHEMBL3877018 | 0.72 | DYRK1A (0.42) | DYRK1AMAPTJAK2TP53HTT | |
| SCHEMBL28094791 | 0.65 | KEAP1 (0.34) | MAPTHTTKDM4EGAAMEN1 | |
| SCHEMBL27896796 | 0.62 | GAA (0.39) | DYRK1AMAPTHTTKDM4EGAA | |
| SCHEMBL27540348 | 0.62 | TSHR (0.36) | MAPTHTTKDM4EGAACYP3A4 | |
| SCHEMBL18226812 | 0.62 | MPL (0.63) | MAPTJAK2TP53HTTKLK7 | |
| SCHEMBL28172033 | 0.60 | TSHR (0.40) | MAPTTP53KDM4EGAACYP3A4 | |
| SCHEMBL28346534 | 0.60 | JAK2 (0.55) | MAPTJAK2TP53HTTKLK7 | |
| SCHEMBL28853012 | 0.60 | HSD17B10 (0.37) | MAPTHTTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |