Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182250 | 0.85 | PDK1 (0.71) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL14041043 | 0.85 | L3MBTL1 (0.61) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL15601887 | 0.84 | HDAC3 (0.72) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7276139 | 0.84 | L3MBTL1 (0.59) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL1817463 | 0.83 | L3MBTL1 (0.58) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL1819254 | 0.83 | L3MBTL1 (0.58) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL20981664 | 0.82 | L3MBTL1 (0.82) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL10756329 | 0.80 | ITGB3 (0.55) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL1815821 | 0.80 | L3MBTL1 (0.55) | L3MBTL1PDK1PDK2PDK3PDK4 | |
| SCHEMBL18262236 | 0.80 | MAPT (0.49) | HDAC1HDAC7HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1944406-A | Indole heterocyclic compounds and intermediate, and synthetic method | SHANGHAI INST ORGANIC CHEM (CN) | 2007-04-11 | — | — | CN | disclosed |