Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14238227 | 0.81 | ACHE (0.41) | TBXAS1KDM4EALDH1A1QPCT | |
| SCHEMBL20555169 | 0.78 | TBXAS1 (0.39) | TBXAS1QPCT | |
| SCHEMBL660885 | 0.78 | TBXAS1 (0.39) | TBXAS1QPCT | |
| SCHEMBL4023237 | 0.76 | TSHR (0.44) | ALDH1A1 | |
| SCHEMBL11456850 | 0.70 | CYP19A1 (0.55) | CYP19A1TBXAS1PDE3BPDE3AHMOX2 | |
| SCHEMBL5030901 | 0.69 | HPGD (0.40) | — | |
| SCHEMBL2338238 | 0.69 | ACHE (0.38) | CYP19A1TBXAS1 | |
| SCHEMBL9456419 | 0.68 | CYP19A1 (0.52) | CYP19A1TBXAS1KDM4EALDH1A1POLB | |
| SCHEMBL5303970 | 0.68 | CYP19A1 (1.00) | CYP19A1TBXAS1POLBHMOX2QPCT | |
| SCHEMBL2336242 | 0.66 | TBXAS1 (0.37) | CYP19A1TBXAS1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906160-A | Imidazole derivatives, processes for preparing them and their uses | UCB SA (BE) | 2007-01-31 | — | — | CN | claimed |