SCHEMBL27673333

SCHEMBL27673333

CCCC(N)(N)c1ccc(NC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
ESR1 P03372 6/20 0.36
ESR2 Q92731 3/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
TSHR P16473 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
APP P05067 4/20 0.32
AR P10275 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.31
RECQL P46063 2/20 0.31
HSD17B10 Q99714 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22043357 0.78 KIF11 (0.44) KIF11ESR1ESR2CA12CA1
SCHEMBL27642296 0.77 MAPT (0.41) KIF11ESR1ESR2CA12CA1
SCHEMBL19234491 0.76 KIF11 (0.42) KIF11ESR1ESR2TSHRADRA2A
SCHEMBL9756593 0.74 KCNN4 (0.46) KIF11
Ammonia Solution, Strong SCHEMBL7144895 0.72 KCNN4 (0.45) KIF11TSHRLMNACYP3A4
SCHEMBL459552 0.71 KIF11 (0.41) KIF11CA12CA1CA2TSHR
SCHEMBL13451559 0.71 TSHR (0.43) KIF11ESR1ESR2TSHRAR
SCHEMBL25007291 0.68 KIF11 (0.47) KIF11CA12CA1CA2TSHR
SCHEMBL8170446 0.68 MEN1 (0.38) ESR1ESR2ARMEN1KMT2A
Butane SCHEMBL10456574 0.67 ALDH1A1 (0.42) CA12CA1CA2TSHRADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100581528-C Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester OREAL 2010-01-20 CN disclosed
CN-1927154-A Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester OREAL (FR) 2007-03-14 CN disclosed