Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 9/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199192 | 0.92 | MLNR (0.51) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL10065840 | 0.90 | PRMT1 (0.59) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL13896297 | 0.86 | MLNR (0.55) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL13452450 | 0.86 | PRMT1 (0.56) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL5179900 | 0.85 | PRMT1 (0.70) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL2739556 | 0.85 | PRMT1 (0.70) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL13813704 | 0.85 | PRMT1 (0.70) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL5179902 | 0.85 | PRMT1 (0.70) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL14271330 | 0.85 | PRMT1 (0.65) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL761512 | 0.84 | PRMT1 (0.54) | PRMT1PRMT5PRMT8BLMMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216769-B2 | Negative working, heat sensitive lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-07-10 | — | — | US | disclosed |
| US-8178282-B2 | Heat-sensitive imaging element | AGFA GRAPHICS NV (BE) | 2012-05-15 | — | — | US | disclosed |
| US-8133657-B2 | Method for making a lithographic printing plate | AGFA GRAPHICS NV (BE) | 2012-03-13 | — | — | US | disclosed |
| US-20100040976-A1 | HEAT-SENSITIVE IMAGING ELEMENT | AGFA GRAPHICS NV (BE) | 2010-02-18 | — | — | US | disclosed |
| US-20090258314-A1 | NEGATIVE WORKING, HEAT SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2009-10-15 | — | — | US | disclosed |
| US-20090155722-A1 | METHOD FOR MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040976-A1 | HEAT-SENSITIVE IMAGING ELEMENT | HEATR1, HEATR6, HSPA8 | PRMT1 4821/4885PRMT5 4771/4885PRMT8 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.