Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655230 | 0.90 | GRM2 (0.38) | GRM2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL28759720 | 0.90 | GRM2 (0.39) | CNR2GRM2GPBAR1SLC2A1PTGIR | |
| SCHEMBL27655235 | 0.87 | GRM2 (0.41) | GRM2CCR5MEN1HPGDKMT2A | |
| SCHEMBL27675253 | 0.84 | TP53 (0.35) | CNR2GRM2GPBAR1SLC2A1CXCR3 | |
| SCHEMBL27675132 | 0.79 | GRM2 (0.43) | GRM2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL27655214 | 0.75 | GRM2 (0.42) | GRM2MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL27655238 | 0.74 | GRM2 (0.39) | GRM2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL27675159 | 0.73 | PDE4A (0.43) | GRM2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL2908377 | 0.72 | LTC4S (0.42) | GRM2SLC2A1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL27655289 | 0.71 | GRM2 (0.40) | GRM2MEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922144-A | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs | MEMORY PHARM CORP (US) | 2007-02-28 | — | — | CN | disclosed |