Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693258 | 0.77 | HSD17B10 (0.41) | HSD17B10HTTKDM4ELMNAALDH1A1 | |
| SCHEMBL27675263 | 0.76 | HTT (0.38) | HSD17B10HTTCYP3A4KDM4ELMNA | |
| SCHEMBL27676693 | 0.75 | PPARA (0.31) | — | |
| Fluoromethane SCHEMBL27676699 | 0.75 | HTT (0.37) | HSD17B10HTTCYP3A4KDM4ELMNA | |
| SCHEMBL21503563 | 0.68 | GABRA1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL28714983 | 0.67 | PTGDR2 (0.36) | SMN1; SMN2KDM4EALOX5APFEN1AAK1 | |
| SCHEMBL16741102 | 0.66 | KDM4E (0.47) | HSD17B10HTTCYP3A4KDM4ELMNA | |
| SCHEMBL1135126 | 0.66 | ALDH1A1 (0.34) | HSD17B10SMN1; SMN2CYP3A4KDM4EABCB11 | |
| SCHEMBL20145921 | 0.65 | KDM4E (0.45) | HSD17B10KDM4ELMNAESR1CYP2C9 | |
| SCHEMBL27589909 | 0.64 | GABRA1 (0.41) | HSD17B10SMN1; SMN2CYP3A4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-88100828-A | Substituted 2, 6-substituted pyridine compounds | — | 1988-08-24 | — | — | CN | disclosed |