Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675261 | 0.77 | HSD17B10 (0.35) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL17706563 | 0.75 | KDM4E (0.45) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL16741102 | 0.72 | KDM4E (0.47) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL27693260 | 0.71 | HTT (0.43) | HSD17B10KDM4EHPGDHTTMAPT | |
| SCHEMBL16265058 | 0.70 | KDM4E (0.59) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL8685294 | 0.70 | KDM4E (0.41) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL8685106 | 0.70 | ALDH1A1 (0.41) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL28257885 | 0.69 | NOS2 (0.46) | HSD17B10KDM4EHTTMAPTLMNA | |
| SCHEMBL27832795 | 0.69 | ALDH1A1 (0.44) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL25405415 | 0.68 | LMNA (0.43) | HSD17B10KDM4EHTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-88100828-A | Substituted 2, 6-substituted pyridine compounds | — | 1988-08-24 | — | — | CN | disclosed |