Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407396 | 0.79 | NFE2L2 (0.41) | NFE2L2ACHEMAOBSLC6A4SLC6A2 | |
| SCHEMBL14541816 | 0.76 | ACHE (0.58) | ACHESLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11667681 | 0.75 | MAOB (0.49) | NFE2L2MAOBHPGDMRGPRX4 | |
| SCHEMBL7024203 | 0.75 | — | — | |
| SCHEMBL166269 | 0.75 | — | — | |
| SCHEMBL29635683 | 0.75 | — | — | |
| SCHEMBL7938427 | 0.74 | MAPT (0.46) | NFE2L2ACHEMAOBSLC6A4SLC6A2 | |
| Iodide SCHEMBL27998185 | 0.73 | NFE2L2 (0.66) | NFE2L2ACHEMAOBRELANPC1 | |
| Water SCHEMBL28234339 | 0.73 | NFE2L2 (0.66) | NFE2L2ACHEMAOBRELANPC1 | |
| Ammonia Solution, Strong SCHEMBL4264966 | 0.73 | NFE2L2 (0.66) | NFE2L2ACHEMAOBRELANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006061-A | 1,5-diphenylpyrazoles | MERCK PATENT GMBH (DE) | 2007-07-25 | — | — | CN | disclosed |