Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936376 | 0.82 | ALDH1A1 (0.52) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL14218312 | 0.82 | CA12 (0.47) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL4644424 | 0.82 | ALDH1A1 (0.47) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL125503 | 0.81 | TDP1 (0.52) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL24113347 | 0.81 | TDP1 (0.44) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL9972921 | 0.81 | TDP1 (0.44) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL6939520 | 0.81 | TDP1 (0.44) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL16270955 | 0.80 | MAOA (0.49) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL523837 | 0.79 | CA2 (0.59) | MAOAMAOBTDP1MEN1KMT2A | |
| SCHEMBL3187413 | 0.79 | TDP1 (0.50) | MAOAMAOBTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100368401-C | Cyanoguanidine prodrugs | LEO PHARMA AS (DK) | 2008-02-13 | — | — | CN | disclosed |