Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169471 | 0.85 | ALOX15 (0.41) | HSP90AA1MAPTMAPK14HTTHSD17B10 | |
| SCHEMBL1628677 | 0.84 | HSP90AA1 (0.51) | HSP90AA1POLBGAANR3C2 | |
| SCHEMBL1631613 | 0.80 | HSP90AA1 (0.46) | HSP90AA1MAPTHSD17B10 | |
| SCHEMBL1630156 | 0.75 | HSP90AA1 (0.49) | HSP90AA1NR3C2 | |
| SCHEMBL1630434 | 0.74 | HSP90AA1 (0.60) | HSP90AA1MAPTMAPK14NR3C2 | |
| SCHEMBL1629695 | 0.74 | ALDH1A1 (0.47) | HSP90AA1MAPTHTTGAAKDM4C | |
| SCHEMBL1629044 | 0.71 | HSP90AA1 (0.40) | HSP90AA1MAPTPOLBNR3C2PTGER1 | |
| SCHEMBL15049636 | 0.71 | GAA (0.45) | HSP90AA1MAPTMAPK14GAAKDM5A | |
| SCHEMBL5168993 | 0.70 | NPC1 (0.47) | HSP90AA1MAPTGAAKDM5AKDM4C | |
| SCHEMBL5167995 | 0.68 | HSP90AA1 (0.40) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006061-A | 1,5-diphenylpyrazoles | MERCK PATENT GMBH (DE) | 2007-07-25 | — | — | CN | disclosed |