Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049763 | 0.86 | HSP90AA1 (0.37) | HSP90AA1 | |
| SCHEMBL1630156 | 0.77 | HSP90AA1 (0.49) | HSP90AA1 | |
| SCHEMBL1629695 | 0.76 | ALDH1A1 (0.47) | HSP90AA1SMN1; SMN2 | |
| SCHEMBL1630434 | 0.72 | HSP90AA1 (0.60) | HSP90AA1CARM1 | |
| SCHEMBL1628677 | 0.72 | HSP90AA1 (0.51) | HSP90AA1 | |
| SCHEMBL1631613 | 0.71 | HSP90AA1 (0.46) | HSP90AA1SMN1; SMN2 | |
| SCHEMBL27675342 | 0.68 | HSP90AA1 (0.42) | HSP90AA1 | |
| SCHEMBL1219216 | 0.68 | HSP90AA1 (0.62) | HSP90AA1 | |
| SCHEMBL1218554 | 0.67 | HSP90AA1 (0.42) | HSP90AA1 | |
| SCHEMBL2095516 | 0.67 | L3MBTL1 (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776346-B1 | 1,5-Diphenylpyrazoles | MERCK PATENT GMBH (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-1776346-A1 | 1,5-DIPHENYLPYRAZOLES | Merck Patent GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018082-A1 | 1,5-DIPHENYLPYRAZOLES | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |