Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77607 | 0.82 | TSHR (0.39) | TSHRTDP1NPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL9808521 | 0.80 | TSHR (0.39) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL6455092 | 0.79 | NPC1 (0.38) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL17288627 | 0.79 | MEN1 (0.51) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL27811270 | 0.76 | MEN1 (0.38) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL27811527 | 0.76 | TRPA1 (0.38) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL10346414 | 0.76 | CYP1A2 (0.38) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL8749377 | 0.76 | NPC1 (0.40) | TSHRMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL6131994 | 0.76 | MEN1 (0.41) | TSHRMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL11247443 | 0.74 | TSHR (0.46) | TSHRHTR2AHRH1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848975-B | Phosphorylated protein, intracellular delivery system based on phosphorylated protein, preparation method and application | 苏州大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-111848975-A | Phosphorylated protein, intracellular delivery system based on phosphorylated protein, preparation method and application | 苏州大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-101006119-A | Click chemistry pathways for triazole dendrimers | SCRIPPS RESEARCH INST (US) | 2007-07-25 | — | — | CN | disclosed |