SCHEMBL8749377

SCHEMBL8749377

C#CCOC(O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
LMNA P02545 3/20 0.38
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
MAPK1 P28482 1/20 0.34
AOC3 Q16853 4/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27991493 0.80 TSHR (0.47) LMNATSHRKDM4EL3MBTL1CYP1A2
SCHEMBL17288627 0.79 MEN1 (0.51) LMNATSHRKDM4ECYP1A2CYP2D6
SCHEMBL6455092 0.79 NPC1 (0.38) NPC1LMNATSHRCYP1A2CYP3A4
SCHEMBL27811527 0.76 TRPA1 (0.38) NPC1LMNATSHRCYP1A2CYP3A4
SCHEMBL27675472 0.76 TSHR (0.39) NPC1LMNATSHRKDM4ECYP1A2
SCHEMBL27811270 0.76 MEN1 (0.38) NPC1LMNATSHRCYP1A2CYP3A4
SCHEMBL10346414 0.76 CYP1A2 (0.38) NPC1LMNATSHRCYP1A2CYP3A4
SCHEMBL28091302 0.74 TRPA1 (0.39) NPC1TSHRCYP1A2CYP3A4CYP2D6
SCHEMBL27259770 0.73 TAAR1 (0.41) LMNATSHRKDM4ECYP1A2CYP3A4
SCHEMBL28821628 0.73 KMT2A (0.36) NPC1LMNATSHRKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384934-B Double-grafted polymer with main chain containing cyclic structure and preparation method thereof 苏州大学 2021-01-29 CN claimed
CN-110678500-B Photo-or thermosetting method and curable resin composition 富士胶片和光纯药株式会社 2022-10-14 CN disclosed
CN-111848975-B Phosphorylated protein, intracellular delivery system based on phosphorylated protein, preparation method and application 苏州大学 2022-07-19 CN disclosed
CN-108602955-B Photocuring method, compound used in photocuring method, and composition 富士胶片和光纯药株式会社 2021-08-06 CN disclosed
CN-109384934-B Double-grafted polymer with main chain containing cyclic structure and preparation method thereof 苏州大学 2021-01-29 CN disclosed
CN-111848975-A Phosphorylated protein, intracellular delivery system based on phosphorylated protein, preparation method and application 苏州大学 2020-10-30 CN disclosed
CN-110678500-A Photo-or thermosetting method and curable resin composition 富士胶片和光纯药株式会社 2020-01-10 CN disclosed
EP-0488817-B1 Heterofunctional macromers and polymers derived therefrom NIPPON PAINT CO LTD (JP) 1997-03-26 EP disclosed
US-5239031-A Heterofunctional macromer compound, its preparation and polymer derived therefrom NIPPON PAINT CO., LTD. (JP) 1993-08-24 US disclosed
US-5239032-A Heterofunctional macromer compound, its preparation and polymer derived therefrom NIPPON PAINT CO., LTD. (JP) 1993-08-24 US disclosed
US-5191032-A HETEROFUNCTIONAL MACROMER COMPOUND, ITS PREPARATION AND POLYMER DERIVED THEREFROM NIPPON PAINT CO., LTD. (JP) 1993-03-02 US disclosed
EP-0488817-A2 Heterofunctional macromers and polymers derived therefrom NIPPON PAINT CO., LTD. (JP) 1992-06-03 EP disclosed