Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821628 | 0.88 | KMT2A (0.36) | NPC1MEN1KMT2AMAPTHTR2A | |
| SCHEMBL26661470 | 0.84 | NPC1 (0.35) | NPC1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL17288627 | 0.83 | MEN1 (0.51) | MEN1KMT2AHTR2ASMN1; SMN2CYP1A2 | |
| SCHEMBL3175966 | 0.81 | CYP3A4 (0.44) | NPC1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11555379 | 0.81 | PPARG (0.38) | TSHRMAOA | |
| SCHEMBL10346414 | 0.79 | CYP1A2 (0.38) | NPC1MEN1KMT2AHTR2ATAAR1 | |
| SCHEMBL76084 | 0.79 | LMNA (0.38) | MEN1KMT2ASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL8749377 | 0.79 | NPC1 (0.40) | NPC1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11314272 | 0.79 | PYCR1 (0.35) | NPC1MEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL27811527 | 0.79 | TRPA1 (0.38) | NPC1MEN1KMT2AMAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546371-A1 | SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031405-A1 | SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2004-04-15 | — | — | WO | disclosed |