Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 7/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675572 | 0.94 | ACHE (0.47) | PDE5AACHE | |
| SCHEMBL27675479 | 0.92 | PDE11A (0.41) | PDE5APDE11AACHE | |
| SCHEMBL28759761 | 0.91 | PDE11A (0.42) | PDE5APDE11AACHE | |
| SCHEMBL6709442 | 0.90 | PDE5A (0.43) | PDE5APDE11AACHEBCDIN3D | |
| SCHEMBL6708393 | 0.90 | ACHE (0.44) | PDE5APDE11AACHEBCDIN3D | |
| SCHEMBL27675443 | 0.89 | PDE5A (0.45) | PDE5APDE11ABCDIN3D | |
| SCHEMBL6709568 | 0.88 | ACHE (0.44) | PDE5APDE11AACHEBCDIN3D | |
| SCHEMBL7096128 | 0.87 | PDE5A (0.43) | PDE5APDE11AACHEBCDIN3D | |
| SCHEMBL6708213 | 0.87 | ACHE (0.43) | PDE5APDE11AACHEBCDIN3D | |
| SCHEMBL6706661 | 0.87 | PDE5A (0.42) | PDE5APDE11AACHEBCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |