Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675511 | 0.94 | PDE5A (0.41) | ACHEPDE5A | |
| SCHEMBL27675431 | 0.90 | ACHE (0.48) | ACHEAPPTNFNOD1BCHE | |
| SCHEMBL27655444 | 0.89 | ACHE (0.47) | ACHEAPPTNFNOD1BCHE | |
| SCHEMBL27655552 | 0.87 | ACHE (0.45) | ACHEAPPTNFNOD1BCHE | |
| SCHEMBL27675500 | 0.86 | ACHE (0.45) | ACHEAPPTNFNOD1BCHE | |
| SCHEMBL27675479 | 0.86 | PDE11A (0.41) | ACHEPDE5A | |
| SCHEMBL28759761 | 0.84 | PDE11A (0.42) | ACHEPDE5A | |
| SCHEMBL27655435 | 0.84 | ACHE (0.42) | ACHEAPPTNFNOD1BCHE | |
| SCHEMBL27655551 | 0.84 | KDM4E (0.38) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL27675416 | 0.84 | ACHE (0.41) | ACHEAPPPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |