Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28194974 | 0.79 | KMT2A (0.47) | ELANE | |
| SCHEMBL28050425 | 0.78 | SLC6A1 (0.45) | CYP2D6NOS2TSHR | |
| SCHEMBL27861553 | 0.73 | — | — | |
| SCHEMBL28816547 | 0.72 | — | — | |
| SCHEMBL5729552 | 0.70 | NPC1 (0.31) | — | |
| SCHEMBL27718907 | 0.69 | FABP7 (0.36) | — | |
| Proline SCHEMBL27675583 | 0.68 | MEN1 (0.40) | DPP4DPP8SCN4ADPP9ELANE | |
| SCHEMBL23356900 | 0.68 | DPP4 (0.49) | CYP3A4CYP2D6CYP1A2CYP2C19DPP4 | |
| SCHEMBL4447785 | 0.68 | DPP4 (0.49) | CYP3A4CYP2D6CYP1A2CYP2C19DPP4 | |
| SCHEMBL2016284 | 0.68 | DPP4 (0.49) | CYP3A4CYP2D6CYP1A2CYP2C19DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1953763-A | Y4 selective receptor agonists for therapeutic intervention | 7TM PHARMA AS (DK) | 2007-04-25 | — | — | CN | claimed |
| CN-105228642-A | Compositions and methods for inhibiting tumor cells by inhibiting transcription factor ATF5 | TRUSTEES OF COLUMBIA UNVERSITY IN THE CITY OF NEW YORK | 2016-01-06 | — | — | CN | disclosed |
| CN-101035568-A | Combination therapy using transferrin fusion proteins comprising GLP-1 | BIOREXIS PHARMACEUTICAL CORP (US) | 2007-09-12 | — | — | CN | disclosed |
| CN-1953763-A | Y4 selective receptor agonists for therapeutic intervention | 7TM PHARMA AS (DK) | 2007-04-25 | — | — | CN | disclosed |
| CN-1933848-A | Y2 selective receptor agonists for therapeutic intervention | 7TM PHARMA AS (DK) | 2007-03-21 | — | — | CN | disclosed |