SCHEMBL27675641

SCHEMBL27675641

C=Cc1ccc(C(O)c2ccc3c(c2)OCO3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PGR P06401 1/20 0.46
AR P10275 1/20 0.46
GABRA1 P14867 1/20 0.46
MAOA P21397 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46
KDR P35968 1/20 0.46
GABRB2 P47870 1/20 0.46
SLC6A3 Q01959 1/20 0.46
MAPK1 P28482 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP3A4 P08684 4/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 3/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1599758 0.86 CYP3A4 (0.54) ALDH1A1MAPK1SMN1; SMN2CYP3A4CYP1A2
SCHEMBL477457 0.81 MAPK1 (0.57) ALDH1A1MAPK1SMN1; SMN2CYP3A4CYP1A2
SCHEMBL29399800 0.79 ALDH1A1 (0.64) HSD17B10ALDH1A1TDP1PGRAR
SCHEMBL81382 0.79 ALDH1A1 (0.64) HSD17B10ALDH1A1TDP1PGRAR
SCHEMBL6869336 0.78 CYP3A4 (0.46) HSD17B10ALDH1A1TDP1PGRAR
Hydrogen Sulfide SCHEMBL30782703 0.77 ALDH1A1 (0.62) HSD17B10ALDH1A1TDP1PGRAR
Hydrogen Sulfide SCHEMBL29194396 0.77 ALDH1A1 (0.62) HSD17B10ALDH1A1TDP1PGRAR
SCHEMBL4816680 0.76 KMT2A (0.63) ALDH1A1SMN1; SMN2CYP3A4CYP1A2MAPT
SCHEMBL4825484 0.75 PTGS1 (0.58) SLC6A2SLC6A3MAPK1CYP3A4CYP1A2
SCHEMBL18626121 0.75 CYP3A4 (0.54) ALDH1A1MAPK1SMN1; SMN2CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-86100669-A The synthetic organic polymers that is used for selective flocculating floatation of titanium and iron ores 1987-08-05 CN disclosed