Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488390 | 0.91 | CASP2 (0.66) | CASP2CSNK1DDYRK1AFSCN1NPC1 | |
| SCHEMBL11258414 | 0.89 | CASP2 (0.64) | CASP2CSNK1DDYRK1AFSCN1NPC1 | |
| SCHEMBL4867128 | 0.84 | CASP2 (0.62) | CASP2CSNK1DDYRK1AFSCN1NPC1 | |
| SCHEMBL27173084 | 0.82 | DYRK1A (0.70) | CASP2CSNK1DDYRK1AFSCN1NPC1 | |
| SCHEMBL29477209 | 0.82 | DYRK1A (0.70) | CASP2CSNK1DDYRK1AFSCN1NPC1 | |
| SCHEMBL11257864 | 0.81 | CASP2 (0.56) | CASP2DYRK1AFSCN1NPC1RAB9A | |
| SCHEMBL20679616 | 0.80 | CASP2 (0.69) | CASP2CSNK1DNPC1RAB9AMAPT | |
| SCHEMBL17251987 | 0.78 | PDPK1 (0.68) | CASP2CSNK1DDYRK1ANPC1RAB9A | |
| SCHEMBL29477216 | 0.78 | RAB9A (0.72) | CASP2CSNK1DDYRK1ANPC1RAB9A | |
| SCHEMBL30849479 | 0.78 | RAB9A (0.68) | CASP2CSNK1DDYRK1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100500665-C | Triazolo-pyrimido-thioacetamide compounds, preparation method and uses | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-1962662-A | Triazolo-pyrimido-thioacetamide compounds, preparation method and uses | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-05-16 | — | — | CN | disclosed |