Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28190708 | 0.84 | ALDH1A1 (0.47) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL29435252 | 0.79 | KDM4E (0.46) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL11357634 | 0.79 | KDM4E (0.46) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7308873 | 0.78 | CTSD (0.43) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8527732 | 0.78 | CTSD (0.43) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL9831434 | 0.76 | CTSD (0.53) | KDM4EKMT2AALDH1A1CTSDSTAT3 | |
| SCHEMBL27607926 | 0.76 | CA1 (0.44) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL31093097 | 0.74 | CA1 (0.52) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL1433789 | 0.74 | CA1 (0.52) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL2770115 | 0.74 | CA1 (0.52) | CTSDCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824952-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-04-28 | — | — | EP | claimed |
| US-20080306170-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | claimed |
| EP-1824952-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2007-08-29 | — | — | EP | claimed |
| WO-2006060931-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2006-06-15 | — | — | WO | claimed |
| US-9102899-B2 | Organic compounds | GIVAUDAN SA (CH) | 2015-08-11 | — | — | US | disclosed |
| EP-1824952-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-04-28 | — | — | EP | disclosed |
| US-20080306170-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1824952-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006060931-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306170-A1 | Organic Compounds | PNN, TRPA1, PAOX | KDM4E 2158/4885KMT2A 1920/4885MEN1 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.