Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067602 | 0.81 | CYP1A2 (0.42) | PIM2POLBKDM4EMEN1KMT2A | |
| SCHEMBL2638128 | 0.77 | KDM4E (0.47) | PIM2HCAR3KDM4ESMN1; SMN2ALOX15 | |
| SCHEMBL11508947 | 0.76 | NPC1 (0.46) | HCAR3POLBKDM4ESMN1; SMN2ALOX15 | |
| SCHEMBL16132008 | 0.75 | HRH3 (0.35) | PIM2POLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL13279964 | 0.73 | HRH3 (0.41) | PIM2KMT2ACYP1A2HRH3 | |
| SCHEMBL6471080 | 0.72 | NNMT (0.41) | HCAR3MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL13466379 | 0.71 | HRH3 (0.33) | PIM2POLBALDH1A1HRH3 | |
| SCHEMBL698657 | 0.69 | KDM4E (0.52) | KDM4ESMN1; SMN2ALOX15MEN1KMT2A | |
| SCHEMBL14207379 | 0.67 | MEN1 (0.46) | HCAR3POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2638747 | 0.67 | KDM4E (0.50) | HCAR3KDM4EALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100345853-C | Pyrazolopyrimidine compound and method for producing the same | TANABE SEIYAKU CO (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-1742013-A | Pyrazolopyrimidine compound and method for producing the same | TANABE SEIYAKU CO (JP) | 2006-03-01 | — | — | CN | disclosed |