SCHEMBL698657

SCHEMBL698657

O=C(O)c1ccc(C(=O)O)nn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.52
TSHR P16473 3/20 0.52
ALOX15 P16050 3/20 0.52
ACMSD Q8TDX5 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
P4HTM Q9NXG6 5/20 0.50
P4HA1 P13674 1/20 0.50
MIF P14174 1/20 0.50
ALDH1A1 P00352 4/20 0.48
MGAM O43451 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
NAPRT Q6XQN6 3/20 0.46
LMNA P02545 2/20 0.46
HIF1A Q16665 1/20 0.43
KDM6B O15054 1/20 0.42
TET3 O43151 1/20 0.42
KDM4A O75164 1/20 0.42
BBOX1 O75936 1/20 0.42
MAPT P10636 1/20 0.42
KDM5A P29375 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL23496608 0.94 KDM4E (0.48) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL1427584 0.87 KDM4E (0.42) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL3174349 0.87 NNMT (0.57) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL31058098 0.87 KCNJ1 (0.46) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL2177672 0.84 GABRP (0.43) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL10963802 0.84 KDM4E (0.41) KDM4ETSHRALOX15ACMSDTDP1
Water SCHEMBL2130375 0.84 KDM4E (0.41) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL380569 0.84 JUN (0.45) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL3889503 0.84 KDM4E (0.42) KDM4ETSHRALOX15ACMSDTDP1
SCHEMBL15921063 0.84 KDM4E (0.48) KDM4ETSHRALOX15ACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836101-A Perovskite solar cell based on diamine molten salt surface modification and preparation method thereof 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN claimed
CN-117797875-A Preparation method of zirconium-based metal organic framework-based photocatalytic material and light stability research method thereof 中国科学技术大学 2024-04-02 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-8653048-B2 Prodrugs based on gemcitabine structure and synthetic methods and applications thereof SANLUGEN PHARMATECH LTD. (CN) 2014-02-18 US claimed
CN-102428093-A Prodrugs based on gemcitabine structure as well as synthetic method and application thereof SANLUGEN PHARMATECH LTD 2012-04-25 CN claimed
US-20120088908-A1 Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof SANLUGEN PHARMATECH LTD. (CN) 2012-04-12 US claimed
EP-2423215-A1 PRODRUGS BASED ON GEMCITABINE STRUCTURE AS WELL AS SYNTHETIC METHOD AND APPLICATION THEREOF Sanlugen Pharmatech Ltd. (CN) 2012-02-29 EP claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-1529247-A1 USE OF SALTS OF LAYERED DOUBLE HYDROXIDES Clariant GmbH (DE) 2005-05-11 EP claimed
WO-2004019138-A1 USE OF SALTS OF LAYERED DOUBLE HYDROXIDES CLARIANT GMBH (DE) 2004-03-04 WO claimed
US-20260078113-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORP (US) 2026-03-19 US disclosed
US-12516044-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2026-01-06 US disclosed
US-20250154143-A1 PRODRUGS FOR USE IN THE TREATMENT OF TISSUE DAMAGE UCL BUSINESS LTD (GB) 2025-05-15 US disclosed
CN-119836101-A Perovskite solar cell based on diamine molten salt surface modification and preparation method thereof 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN disclosed
WO-2001007415-A1 METHOD OF PRODUCING PYRIDAZINE-3,6-DICARBOXYLIC ACID ESTERS LONZA AG (CH) 2001-02-01 WO disclosed
EP-0603557-B1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM CO (US) 1997-07-30 EP disclosed
US-5461126-A Process of polymerizing olefins using organonickel catalyst compositions PHILLIPS PETROLEUM COMPANY (US) 1995-10-24 US disclosed
US-5332708-A Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound PHILLIPS PETROLEUM COMPANY (US) 1994-07-26 US disclosed
EP-0603557-A1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM COMPANY (US) 1994-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088908-A1 Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof TYMP, DCTD, GLS2 KDM4E 2472/4885TSHR 4200/4885ALOX15 2359/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 KDM4E 2504/4885TSHR 4385/4885ALOX15 914/4885
US-20260078113-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS MSR1, NR3C1, CCR1 KDM4E 4270/4885TSHR 113/4885ALOX15 748/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA KDM4E 1109/4885TSHR 2885/4885ALOX15 383/4885
US-20250154143-A1 PRODRUGS FOR USE IN THE TREATMENT OF TISSUE DAMAGE CYP2B6, CBR3, CYP2A6 KDM4E 4634/4885TSHR 86/4885ALOX15 1245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.