SCHEMBL27679

SCHEMBL27679

Cc1ccc(S(=O)(=O)N(C(N)=O)c2ccc(Cc3ccc(N(C(N)=O)S(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
KDM4E B2RXH2 1/20 0.54
MAPT P10636 6/20 0.51
TP53 P04637 5/20 0.51
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MCOLN3 Q8TDD5 1/20 0.46
HCRTR2 O43614 1/20 0.46
CNR2 P34972 3/20 0.46
CNR1 P21554 1/20 0.45
THRB P10828 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243993 0.91 LMNA (0.62) LMNAKDM4EMAPTTP53KEAP1
SCHEMBL27991408 0.91 LMNA (0.62) LMNAKDM4EMAPTTP53KEAP1
SCHEMBL8625094 0.87 LMNA (0.49) LMNAKDM4EMAPTTP53KEAP1
SCHEMBL6467690 0.87 KMT2A (0.51) MEN1KMT2ACNR2ALDH1A1
SCHEMBL6244985 0.86 LMNA (0.57) LMNAKDM4EMAPTTP53KEAP1
SCHEMBL6466821 0.86 KMT2A (0.53) LMNAKDM4EMAPTTP53MEN1
SCHEMBL8393106 0.85 LMNA (0.51) LMNAKDM4EMAPTTP53KEAP1
SCHEMBL6244071 0.85 KMT2A (0.57) MAPTMEN1KMT2AGAACNR2
SCHEMBL8620628 0.85 TP53 (0.55) LMNAMAPTTP53KEAP1NFE2L2
SCHEMBL7999295 0.84 LMNA (0.76) LMNAKDM4EMAPTTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148816-B1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER SE AUGUST PAPIERFABRIK (DE) 2020-02-26 EP claimed
US-20190077178-A1 SELF-ADHESIVE, HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-03-14 US claimed
US-10160245-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOHLER SE (DE) 2018-12-25 US claimed
US-9982157-B2 Aqueous laser-sensitive composition for marking substrates DATALASE LTD. (GB) 2018-05-29 US claimed
EP-3219507-A1 SELF-ADHESIVE THERMOSENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2017-09-20 EP claimed
US-20170190199-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOHLER SE (DE) 2017-07-06 US claimed
EP-3148816-A1 HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2017-04-05 EP claimed
US-9267042-B2 Coating composition for marking substrates DATALASE LTD. (GB) 2016-02-23 US claimed
US-20150361289-A1 AQUEOUS LASER-SENSITIVE COMPOSITION FOR MARKING SUBSTRATES DATALASE LTD. (GB) 2015-12-17 US claimed
EP-2829409-A1 THERMAL RECORDING MATERIAL Fine Ace Corporation (JP) 2015-01-28 EP claimed
EP-0949087-A1 Heat-fixable thermosensitive recording material OJI PAPER CO., LTD. (JP) 1999-10-13 EP claimed
EP-0664224-B1 Heat-sensitive recording paper NEW OJI PAPER CO LTD (JP) 1998-04-22 EP claimed
US-5543382-A GLASSINE PAPER, LEUCO DYE AND DEVELOPER NEW OJI PAPER CO., LTD. (JP) 1996-08-06 US claimed
EP-0664224-A2 Heat-sensitive recording paper NEW OJI PAPER CO., LTD. (JP) 1995-07-26 EP claimed
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed