Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662172 | 0.88 | TP53 (0.51) | TP53LMNAALDH1A1USP2KEAP1 | |
| SCHEMBL9478142 | 0.86 | TP53 (0.73) | TP53LMNAALDH1A1USP2KEAP1 | |
| SCHEMBL27679 | 0.85 | LMNA (0.54) | TP53LMNAALDH1A1KEAP1NFE2L2 | |
| SCHEMBL6462883 | 0.84 | PTGES (0.52) | LMNA | |
| SCHEMBL6466488 | 0.84 | SAE1 (0.44) | TP53LMNAALDH1A1KEAP1NFE2L2 | |
| SCHEMBL6467690 | 0.83 | KMT2A (0.51) | ALDH1A1F2HPGDKMT2ATAS2R14 | |
| SCHEMBL6466821 | 0.82 | KMT2A (0.53) | TP53LMNAALDH1A1MAPTHPGD | |
| SCHEMBL6244071 | 0.81 | KMT2A (0.57) | ALDH1A1MAPTGAAF2HPGD | |
| SCHEMBL6465397 | 0.81 | CA1 (0.52) | ALDH1A1KEAP1KMT2A | |
| SCHEMBL6470650 | 0.81 | CA12 (0.50) | TP53LMNAALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792755-B1 | Thermosensitive recording material | OJI PAPER CO (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0604832-B1 | Thermosensitive recording material | OJI PAPER CO (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0792755-A1 | Thermosensitive recording material | OJI PAPER COMPANY LIMITED (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-5612280-A | AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS | NEW OJI PAPER CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |
| EP-0604832-A2 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |