SCHEMBL6467690

SCHEMBL6467690

NC(=O)N(c1ccc(Cc2ccc(N(C(N)=O)S(=O)(=O)c3ccc(Cc4ccccc4)cc3)cc2)cc1)S(=O)(=O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CA12 O43570 1/20 0.47
CA14 Q9ULX7 1/20 0.47
PLA2G10 O15496 1/20 0.47
PLA2G2A P14555 1/20 0.47
TAS2R14 Q9NYV8 7/20 0.43
MEN1 O00255 2/20 0.43
PTGES O14684 3/20 0.43
ALOX5 P09917 1/20 0.43
ALDH1A1 P00352 1/20 0.42
F2 P00734 1/20 0.42
HPGD P15428 1/20 0.42
ESR1 P03372 1/20 0.42
CNR2 P34972 3/20 0.42
CXCR3 P49682 1/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6244071 0.95 KMT2A (0.57) KMT2ACA1CA2CA9CA12
SCHEMBL6529186 0.93 CA1 (0.51) KMT2ACA1CA2CA9CA12
SCHEMBL6467475 0.90 KMT2A (0.46) KMT2ACA1CA2CA9CA12
SCHEMBL6462883 0.89 PTGES (0.52) PTGESALOX5
SCHEMBL6465397 0.89 CA1 (0.52) KMT2ACA1CA2CA9CA12
SCHEMBL27679 0.87 LMNA (0.54) KMT2AMEN1ALDH1A1CNR2
SCHEMBL6466821 0.84 KMT2A (0.53) KMT2ACA1CA2CA9CA12
SCHEMBL6467529 0.83 CNR2 (0.42) KMT2ACA1CA2CA9CA12
SCHEMBL8837714 0.83 CA12 (0.41) KMT2ACA1CA2CA9CA12
SCHEMBL8620628 0.83 TP53 (0.55) KMT2ATAS2R14ALDH1A1F2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed