Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657614 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL30283493 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL27771387 | 0.85 | LMNA (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL4998342 | 0.85 | LMNA (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL28069455 | 0.84 | LMNA (0.48) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL829972 | 0.83 | KMT2A (0.64) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL20299326 | 0.81 | TSHR (0.52) | ALDH1A1LMNAF2SMN1; SMN2 | |
| SCHEMBL27612334 | 0.81 | CHRNB2 (0.51) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL7671999 | 0.81 | TSHR (0.55) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL27261138 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1964964-A | Piperidine derivatives for the treatment of chemokine mediated diseases | ASTRAZENECA AB (SE) | 2007-05-16 | — | — | CN | disclosed |