Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13288522 | 0.93 | HDAC1 (0.55) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27659497 | 0.83 | HDAC8 (0.57) | HDAC8HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL27659484 | 0.81 | MAPK1 (0.54) | NPC1RAB9AHDAC8HDAC6HDAC1 | |
| SCHEMBL27679562 | 0.81 | FPR2 (0.54) | HDAC8HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL27679616 | 0.80 | HDAC8 (0.56) | RAB9AHDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL27679547 | 0.80 | HDAC8 (0.52) | HDAC8HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL28764302 | 0.79 | HDAC8 (0.58) | HDAC8HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL28760351 | 0.79 | HDAC8 (0.64) | RAB9AHDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL28760350 | 0.79 | HDAC8 (0.52) | HDAC8HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL8271583 | 0.77 | HDAC2 (0.68) | HDAC8HDAC6HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997627-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | claimed |
| CN-1997627-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |