Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708950 | 0.88 | LMNA (0.60) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL27698517 | 0.84 | SLC6A2 (0.52) | SMN1; SMN2HPGDKMT2ASLC6A2SLC6A4 | |
| SCHEMBL7769589 | 0.83 | HTT (0.62) | CXCL8ALDH1A1KDM4EHTTHPGD | |
| SCHEMBL27679498 | 0.83 | LMNA (0.45) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL29084606 | 0.82 | ALDH1A1 (0.56) | CXCL8LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28949692 | 0.81 | CXCL8 (0.51) | CXCL8ALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL10681224 | 0.81 | LMNA (0.53) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| Ethylene Glycol SCHEMBL29185194 | 0.81 | LMNA (0.58) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL27679505 | 0.79 | HTT (0.73) | LMNAALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL27698525 | 0.79 | SMN1; SMN2 (0.51) | LMNAALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |