Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28764344 | 0.76 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL13770623 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL6376833 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL3106152 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL26060560 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL28804740 | 0.73 | — | — | |
| SCHEMBL22944448 | 0.72 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL5805993 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL22944469 | 0.67 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL14104187 | 0.67 | SIGMAR1 (0.38) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1964975-B | Hiv integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-11-30 | — | — | CN | disclosed |
| CN-1964975-A | HIV integrase inhibitors | MERCK & CO INC (US) | 2007-05-16 | — | — | CN | disclosed |