Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.51 |
| ▸ | LOX | P28300 | 7/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964495 | 0.86 | LOXL2 (0.62) | ROCK2LOXL2PLAULOXCFD | |
| Hydrochloric Acid SCHEMBL19953267 | 0.85 | LOXL2 (0.62) | ROCK2LOXL2PLAULOXCFD | |
| SCHEMBL2105735 | 0.84 | PLAU (0.56) | LOXL2PLAUPLGPLATKLKB1 | |
| SCHEMBL15653197 | 0.84 | PTGS1 (0.59) | ROCK2LOXL2PLAULOXPLG | |
| Hydrochloric Acid SCHEMBL6557821 | 0.83 | NT5E (0.59) | ROCK2LOXL2LOX | |
| SCHEMBL1552986 | 0.82 | NT5E (0.62) | ROCK2LOXL2LOXMEN1KMT2A | |
| SCHEMBL15888443 | 0.82 | ROCK2 (0.61) | ROCK2LOXL2PLAULOXPLG | |
| Hydrochloric Acid SCHEMBL5458845 | 0.81 | NT5E (0.61) | ROCK2LOXL2LOXMEN1KMT2A | |
| SCHEMBL15650701 | 0.79 | PTGS1 (0.60) | ROCK2LOXL2LOXMEN1KMT2A | |
| SCHEMBL307678 | 0.78 | ROCK2 (0.67) | ROCK2LOXL2PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960976-A | 4-carbox pyrazole derivates useful as anti-viral agents | SMITHKLINE BEECHAM CORP (US) | 2007-05-09 | — | — | CN | disclosed |